diff --git a/src/qemu/qemu_command.c b/src/qemu/qemu_command.c
index 6cd35f8cb4..e8bfc2964e 100644
--- a/src/qemu/qemu_command.c
+++ b/src/qemu/qemu_command.c
@@ -876,10 +876,21 @@ int qemuDomainPCIAddressEnsureAddr(qemuDomainPCIAddressSetPtr addrs,
                                     virDomainDeviceInfoPtr dev)
 {
     int ret = 0;
-    if (dev->type == VIR_DOMAIN_DEVICE_ADDRESS_TYPE_PCI)
-        ret = qemuDomainPCIAddressReserveAddr(addrs, dev);
-    else
+    if (dev->type == VIR_DOMAIN_DEVICE_ADDRESS_TYPE_PCI) {
+        /* We do not support hotplug multi-function PCI device now, so we should
+         * reserve the whole slot. The function of the PCI device must be 0.
+         */
+        if (dev->addr.pci.function != 0) {
+            qemuReportError(VIR_ERR_INTERNAL_ERROR, "%s",
+                            _("Only PCI device addresses with function=0"
+                              " are supported"));
+            return -1;
+        }
+
+        ret = qemuDomainPCIAddressReserveSlot(addrs, dev->addr.pci.slot);
+    } else {
         ret = qemuDomainPCIAddressSetNextAddr(addrs, dev);
+    }
     return ret;
 }
 
@@ -914,6 +925,36 @@ int qemuDomainPCIAddressReleaseFunction(qemuDomainPCIAddressSetPtr addrs,
     return qemuDomainPCIAddressReleaseAddr(addrs, &dev);
 }
 
+int qemuDomainPCIAddressReleaseSlot(qemuDomainPCIAddressSetPtr addrs, int slot)
+{
+    virDomainDeviceInfo dev;
+    char *addr;
+    int function;
+    int ret = 0;
+
+    dev.addr.pci.domain = 0;
+    dev.addr.pci.bus = 0;
+    dev.addr.pci.slot = slot;
+
+    for (function = 0; function <= QEMU_PCI_ADDRESS_LAST_FUNCTION; function++) {
+        addr = qemuPCIAddressAsString(&dev);
+        if (!addr)
+            return -1;
+
+        if (!virHashLookup(addrs->used, addr)) {
+            VIR_FREE(addr);
+            continue;
+        }
+
+        VIR_FREE(addr);
+
+        if (qemuDomainPCIAddressReleaseFunction(addrs, slot, function) < 0)
+            ret = -1;
+    }
+
+    return ret;
+}
+
 void qemuDomainPCIAddressSetFree(qemuDomainPCIAddressSetPtr addrs)
 {
     if (!addrs)
diff --git a/src/qemu/qemu_command.h b/src/qemu/qemu_command.h
index 4c83182492..d7673adce3 100644
--- a/src/qemu/qemu_command.h
+++ b/src/qemu/qemu_command.h
@@ -160,6 +160,7 @@ int qemuDomainPCIAddressReleaseAddr(qemuDomainPCIAddressSetPtr addrs,
                                     virDomainDeviceInfoPtr dev);
 int qemuDomainPCIAddressReleaseFunction(qemuDomainPCIAddressSetPtr addrs,
                                         int slot, int function);
+int qemuDomainPCIAddressReleaseSlot(qemuDomainPCIAddressSetPtr addrs, int slot);
 
 void qemuDomainPCIAddressSetFree(qemuDomainPCIAddressSetPtr addrs);
 int  qemuAssignDevicePCISlots(virDomainDefPtr def, qemuDomainPCIAddressSetPtr addrs);
diff --git a/src/qemu/qemu_hotplug.c b/src/qemu/qemu_hotplug.c
index e69c1a031e..e330d85b46 100644
--- a/src/qemu/qemu_hotplug.c
+++ b/src/qemu/qemu_hotplug.c
@@ -242,7 +242,8 @@ error:
     if (qemuCapsGet(priv->qemuCaps, QEMU_CAPS_DEVICE) &&
         (disk->info.type == VIR_DOMAIN_DEVICE_ADDRESS_TYPE_PCI) &&
         releaseaddr &&
-        qemuDomainPCIAddressReleaseAddr(priv->pciaddrs, &disk->info) < 0)
+        qemuDomainPCIAddressReleaseSlot(priv->pciaddrs,
+                                        disk->info.addr.pci.slot) < 0)
         VIR_WARN("Unable to release PCI address on %s", disk->src);
 
     if (virSecurityManagerRestoreImageLabel(driver->securityManager,
@@ -314,7 +315,8 @@ cleanup:
         qemuCapsGet(priv->qemuCaps, QEMU_CAPS_DEVICE) &&
         (controller->info.type == VIR_DOMAIN_DEVICE_ADDRESS_TYPE_PCI) &&
         releaseaddr &&
-        qemuDomainPCIAddressReleaseAddr(priv->pciaddrs, &controller->info) < 0)
+        qemuDomainPCIAddressReleaseSlot(priv->pciaddrs,
+                                        controller->info.addr.pci.slot) < 0)
         VIR_WARN("Unable to release PCI address on controller");
 
     VIR_FREE(devstr);
@@ -739,7 +741,8 @@ cleanup:
         qemuCapsGet(priv->qemuCaps, QEMU_CAPS_DEVICE) &&
         (net->info.type == VIR_DOMAIN_DEVICE_ADDRESS_TYPE_PCI) &&
         releaseaddr &&
-        qemuDomainPCIAddressReleaseAddr(priv->pciaddrs, &net->info) < 0)
+        qemuDomainPCIAddressReleaseSlot(priv->pciaddrs,
+                                        net->info.addr.pci.slot) < 0)
         VIR_WARN("Unable to release PCI address on NIC");
 
     if (ret != 0)
@@ -870,7 +873,8 @@ error:
     if (qemuCapsGet(priv->qemuCaps, QEMU_CAPS_DEVICE) &&
         (hostdev->info.type == VIR_DOMAIN_DEVICE_ADDRESS_TYPE_PCI) &&
         releaseaddr &&
-        qemuDomainPCIAddressReleaseAddr(priv->pciaddrs, &hostdev->info) < 0)
+        qemuDomainPCIAddressReleaseSlot(priv->pciaddrs,
+                                        hostdev->info.addr.pci.slot) < 0)
         VIR_WARN("Unable to release PCI address on host device");
 
     qemuDomainReAttachHostdevDevices(driver, &hostdev, 1);
@@ -1257,7 +1261,8 @@ int qemuDomainDetachPciDiskDevice(struct qemud_driver *driver,
     qemuAuditDisk(vm, detach, NULL, "detach", true);
 
     if (qemuCapsGet(priv->qemuCaps, QEMU_CAPS_DEVICE) &&
-        qemuDomainPCIAddressReleaseAddr(priv->pciaddrs, &detach->info) < 0)
+        qemuDomainPCIAddressReleaseSlot(priv->pciaddrs,
+                                        detach->info.addr.pci.slot) < 0)
         VIR_WARN("Unable to release PCI address on %s", dev->data.disk->src);
 
     virDomainDiskRemove(vm->def, i);
@@ -1496,7 +1501,8 @@ int qemuDomainDetachPciControllerDevice(struct qemud_driver *driver,
     }
 
     if (qemuCapsGet(priv->qemuCaps, QEMU_CAPS_DEVICE) &&
-        qemuDomainPCIAddressReleaseAddr(priv->pciaddrs, &detach->info) < 0)
+        qemuDomainPCIAddressReleaseSlot(priv->pciaddrs,
+                                        detach->info.addr.pci.slot) < 0)
         VIR_WARN("Unable to release PCI address on controller");
 
     virDomainControllerDefFree(detach);
@@ -1595,7 +1601,8 @@ int qemuDomainDetachNetDevice(struct qemud_driver *driver,
     qemuAuditNet(vm, detach, NULL, "detach", true);
 
     if (qemuCapsGet(priv->qemuCaps, QEMU_CAPS_DEVICE) &&
-        qemuDomainPCIAddressReleaseAddr(priv->pciaddrs, &detach->info) < 0)
+        qemuDomainPCIAddressReleaseSlot(priv->pciaddrs,
+                                        detach->info.addr.pci.slot) < 0)
         VIR_WARN("Unable to release PCI address on NIC");
 
     virDomainConfNWFilterTeardown(detach);
@@ -1719,7 +1726,8 @@ int qemuDomainDetachHostPciDevice(struct qemud_driver *driver,
     }
 
     if (qemuCapsGet(priv->qemuCaps, QEMU_CAPS_DEVICE) &&
-        qemuDomainPCIAddressReleaseAddr(priv->pciaddrs, &detach->info) < 0)
+        qemuDomainPCIAddressReleaseSlot(priv->pciaddrs,
+                                        detach->info.addr.pci.slot) < 0)
         VIR_WARN("Unable to release PCI address on host device");
 
     if (vm->def->nhostdevs > 1) {